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Dydrogesterone
Clinical data
Trade namesDuphaston, others
AHFS/Drugs.comInternational Drug Names
Routes of administrationBy mouth
Drug classProgestin; Progestogen
ATC codeG03DB01 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability28% [5]
Protein binding? (probably to albumin) [5] [6]
MetabolismHepatic: AKR1C1, AKR1C3, CYP3A4 [3] [4]
Metabolites20α-DHD (exclusively via AKR1C1 and AKRC13) [4]
Elimination half-lifeParent: 5–7 hours [7] Metabolite: 14–17 hours [7]
ExcretionUrine

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